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What is Psilocybin (Magic Mushrooms)?
Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) and psilocin are chemical compounds obtained from certain types of dried or fresh hallucinogenic mushrooms found in Mexico, South America and the southern and northwest regions of the United States. Psilocybin is classified as an indole-alkylamine (tryptamine). . Hallucinogenic (psychedelic) effects are probably due to action on central nervous system serotonin (5-HT) receptors.
There are over 180 species of mushrooms that contain the chemicals psilocybin or psilocin. Like the peyote (mescaline), hallucinogenic mushrooms have been used in native or religious rites for centuries.
“Magic Mushrooms” have long, slender stems which may appear white or greyish topped by caps with dark gills on the underside. Dried mushrooms are usually a reddish rust brown color with isolated areas of off-white. Mushrooms are ingested orally and may be made into a tea or mixed into other foods. The mushrooms may be used as fresh or dried product. Psilocybin has a bitter, unpalatable taste.
A “bad trip”, or a unpleasant or even terrifying experience, may occur with any dose of psilocybin. In general, dried mushrooms contain about 0.2% to 0.4% psilocybin and only trace amounts of psilocin. The typical dose of psilocybin used for recreational purposes varies, with peak effects occurring in 1 to 2 hours, and lasting for about six hours.
Dose and effects can vary considerably depending upon mushroom type, method of preparation, and tolerance of the individual. It can be difficult to determine the exact species of mushroom or how much hallucinogen each mushroom contains. Initial smaller doses and a longer period of time to determine the effects may be a safer option if you choose to use psilocybin for recreational purposes.
Psilocybin effects are similar to those of other hallucinogens, such as mescaline from peyote or LSD. The psychological reaction to psilocybin use include visual and auditory hallucinations and an inability to discern fantasy from reality. Panic reactions and psychosis also may occur, particularly if large doses of psilocybin are ingested.
Hallucinogens that interfere with the action of the brain chemical serotonin may alter:
- sensory perception
- body temperature
- sexual behavior
- muscle control
Physical effects of psychedelic mushrooms may include a feeling of nausea, vomiting, muscle weakness, confusion, and a lack of coordination. Combined use with other substances, such as alcohol and marijuana can heighten, or worsen all of these effects.
Other effects of hallucinogenic drugs can include:
- intensified feelings and sensory experiences
- changes in sense of time (for example, time passing by slowly)
- increased blood pressure, breathing rate, or body temperature
- loss of appetite
- dry mouth
- sleep problems
- mixed senses (such as “seeing” sounds or “hearing” colors)
- spiritual experiences
- feelings of relaxation or detachment from self/environment
- uncoordinated movements
- lowered inhibition
- excessive sweating
- paranoia – extreme and unreasonable distrust of others
- psychosis – disordered thinking detached from reality
Larger psilocybin doses, including an overdose, can lead to intense hallucinogenic effects over a longer period of time. An intense “trip” episode may occur, which may involve panic, paranoia, psychosis, frightful visualizations (“bad trip”), and very rarely death. Memory of a “bad trip” can last a lifetime.mushroom capsule
“Flashbacks”, similar to those occur in some people after using LSD, have also been reported with mushrooms. It is reported that people who use LSD or mescaline can build a cross-tolerance to psilocybin, as well.
Common hallucinogens, with the possible exception of phencyclidine (PCP), are not usually tested for on standard workplace drug screens. However, if desired by legal authorities, medical personnel, or an employer, it is possible to perform laboratory assays that can detect any drug or metabolite, including psilocybin, via advanced techniques.
When tested via urine, the psilocybin mushroom metabolite psilocin can stay in your system for up to 3 days. However, metabolic rate, age, weight, age, medical conditions, drug tolerance, other drugs or medications used, and urine pH of each individual may affect actual detection periods.mushroom capsule
Based on a 2018 survey from SAMHSA’s National Survey on Drug Use and Health (NSDUH), about 5.6 million people aged 12 or older reported using hallucinogens (which may include psilocybin mushrooms) in the year prior to the survey. 2017, that number was roughly 5.1 million. In the survey, hallucinogens include not only psilocybin from mushrooms, but also other psychedelic drugs like LSD, MDMA (Ecstasy, Molly), and peyote (mescaline). In comparison, 43.5 million people used marijuana in the year prior to the 2018 survey.mushroom capsule